Synopsis
The BioSAXS beamline is a highly automated beamline dedicated to the study of proteins, macromolecular complexes, viruses etc., in solution. Samples can be investigated under various conditions (temperature, buffer, pH, kinetics) in a high-throughput manner or a HPLC unit can be used for in-situ (online) purification.
Status:
open
Disciplines
- Life Sciences
- Chemistry
- Medicine
Applications
- Structural biology
- Pharmaceuticals
Techniques
-
BioSAXS - small-angle X-ray scattering (proteins/DNA)
-
SAXS - small-angle X-ray scattering
Beam size
- Minimum (H x V) : 50.0
x 50.0
µm²
-
Maximum (H x V) : 2.0
x 1.0
mm²
Sample environments
- Quartz capillary as a part of automated sample changer allowing temperature variations (from 4 to 60°C)
- HPLC (high performance liquid chromatography) system can be used in parallel with sample changer
Detectors
Pernot P., Theveneau P., Giraud T., Nogueira Fernandes R., Nurizzo D., Spruce D., Surr J., McSweeney S., Round A., Felisaz F., Foedinger L., Gobbo A., Huet J., Villard C. and Cipriani F., "New beamline dedicated to solution scattering from biological macromolecules at the ESRF", Journal of Physics: Conference Series 247 (2010) 012009-1-012009-8.
Unveiling the crystal structure of thermostable dienelactone hydrolase exhibiting activity on terephthalate esters
Almeida D.V., Ciancaglini I., Hernandes Sandano A.L., Roman E.K.B., Brito Andrade V., Nunes A.B., Tramontina R., da Silva V.M., Gabel F., Corrêa T.L.R., Damasio A., Muniz J.R.C., Squina F.M., Garcia W.,
Enzyme and Microbial Technology 180, 110498-1-110498-10 (2024)
An integrative structural study of the human full-length RAD52 at 2.2 Å resolution
Balboni B., Marotta R., Rinaldi F., Milordini G., Varignani G., Girotto S., Cavalli A.,
Communications Biology 7, 956-1-956-12 (2024)
Structural dynamics of the TPR domain of the peroxisomal cargo receptor Pex5 in Trypanosoma
Banasik M., Napolitano V., Blat A., Abdulkarim K., Plewka J., Czaplewski C., Gieldon A., Kozak M., Wladyka B., Popowicz G., Dubin G.,
International Journal of Biological Macromolecules 280, 135510-1-135510-9 (2024)
Diversifying de novo TIM barrels by hallucination
Beck J., Shanmugaratnam S., Höcker B.,
Protein Science 33, e5001-1-e5001-11 (2024)
Hindered intermolecular stacking of anti-parallel telomeric G-quadruplexes
Bertini L., Libera V., Catalini S., Schirò G., Orecchini A., Campanella R., Arciuolo V., Pagano B., Petrillo C., De Michele C., Comez L., Paciaroni A.,
Journal of Chemical Physics 161, 105101-1-105101-7 (2024)
The Arthropoda-specific Tramtrack group BTB protein domains use previously unknown interface to form hexamers
Bonchuk A.N., Balagurov K.I., Baradaran R., Boyko K.M., Sluchanko N.N., Khrustaleva A.M., Burtseva A.D., Arkova O.V., Khalisova K.K., Popov V.O., Naschberger A., Georgiev P.G.,
eLife 13, e96832-1-e96832-25 (2024)
Add this RSS feed to your favorite RSS reader (Thunderbird, Outlook etc...) or install an add-on to your browser, such as RSSPreview for Firefox