69HIGHLIGHTS 2020

Synchrotron X-Ray Boost Delivered by Microbeam Radiation Therapy After Conventional X-Ray Therapy Fractionated in Time Improves F98 Glioma Control, M. Potez (a), A. Bouchet (a,b), M. Flaender (a), C. Rome (c), M. Grotzer (d), M. Krisch (e), V. Djonov (b), J. Balosso (f), E. Brun (a), J.A. Laissue (b) and

R. Serduc (a), Int. J. Radiat. Oncol. Biol. Phys. 107(2), 360-369 (2020); https://doi. org/10.1016/j.ijrobp.2020.02.023. (a) Synchrotron Radiation for Biomedicine Group, Inserm UA7, University of Grenoble Alpes (France) (b) Institute of Anatomy, University of Bern (Switzerland)

(c) Grenoble Institut des Neurosciences, University of Grenoble Alpes (France) (d) Department of Oncology, University Children s Hospital of Zurich (Switzerland) (e) ESRF (f) Department of Radiation-Oncology, Grenoble University Hospital (France)

[1] R. Stupp et al., N. Engl. J. Med. 352, 987 996 (2005). [2] L. Eling et al., Radiother. Oncol. 139, 56-61 (2019).

REVEALING THE CRYSTALLISATION FROM SOLUTION OF LEAD-FREE TIN PEROVSKITES

Mixed organic-inorganic perovskites are promising materials for future photovoltaic applications. Among the most promising, low-toxicity, lead-free perovskites, tin-based perovskites are receiving much attention. Here, the mechanism of crystallisation from solution during spin coating of Sn-based perovskites is investigated in situ using millisecond grazing incidence wide-angle X-ray scattering (GIWAXS).

PRINCIPAL PUBLICATION AND AUTHORS

REFERENCES

Fig. 54: Effect of MRT boost on cell proliferation. a) Representative merged mosaics of an entire tumour immunostained with Ki67 (red) and DAPI (blue) for untreated group (CTRL), after 3 x 6 Gy BB fractions, BB/BB (+ 2 x 8 Gy BB fractions) and BB/MRT (+ 2 x 8 Gy MRT fractions). b) FACS analysis of cell cycle distributions of tumour cells in untreated (black dot pattern), after 3 x 6 Gy BB (black), BB/BB (grey) and BB/MRT (green) groups 7, 12, 15 and 20 days after treatment start. *, **: significantly different values from those of time matched group(s) within the same cycle phase. t-test p < 0.05 and 0.01, respectively. +, ++ and ^, ^^: significantly different from CTRL and T7 irradiated groups (3 x 6 Gy), t-tests, p < 0.05 and 0.01, respectively.

Three-dimensional (3D) perovskite materials with an ABX3 structure (where A is either an organic or an inorganic cation, B is a divalent metal cation, and X is a halide anion) have demonstrated superb properties as light absorbers in photovoltaic devices. Lead (Pb)- based hybrid perovskite solar cells (HPSCs)

have achieved an impressive power conversion efficiency (PCE) of up to 22% [1]; however, lead s toxicity causes concerns for health and the environment. Among the various alternatives to lead, tin (Sn) has great potential, as Sn-based hybrid perovskites display excellent optical and electrical properties such as high absorption