List of classified proteins

In general, a gene which codes for a toxin or a biologically active protein in the physiological mechanisms of the infection or the immunity may be, under certain conditions, a factor of danger whose risk must be examined on a case by case study. The Commission de Génie Génétique (CGG) has established a non-exhaustive list of examples of sequences from categories A and B. The classification into A and B may be modified according to the evolution of knowledge. Concerning toxins; a list is presently being elaboration by the CGG. In the meantime, the CGG will examine case by case the dossiers related to toxins.

Non exhaustive guide of category A and B sequences

I. Viral Sequences

The viral sequences capable of modifying the tropism of a virus under certain experimental conditions (surface proteins such as glycoprotein for example) are considered as being in category B

II. Cellular Sequences

(1) Adjustment possible after examination of the dossier's arguments

(2) All interleukines except IL 10 are in B

III. Toxins

Toxins are considered as being at least type B sequences. A list of toxins is presently being elaborated by the CGG. In the meantime, the experiments are classified on a case-by-case study according to the potential danger conferred by these sequences.

Translation from the French Genetic Engineering Commission Guide