UDM1 - Emerging viral diseases: How can structural studies help to seek remedies?

W E B I N A R

Scientific Organisers	UOC Organiser: Marina Mapelli, European Institute of Oncology, Milano, Italy ESRF Organisers: Eaazhisai Kandiah Christoph Mueller-Dieckmann T. Narayanan
Keynote Speakers	James Naismith, Rosalind Franklin Institute, Oxford, UK Uri Raviv, Hebrew University of Jerusalem, Israel Félix Rey, Institut Pasteur, Paris, France
Administrative Assistant	Claudine Roméro
Contact	udm1-um21@esrf.fr
Format	Zoom Webinar
Replay the talks:	RAVIV Uri - Mechanism of Virus Assembly and Disassembly SAN MARTIN Carmen - Latest Structural Insights on Adenoviruses, Overlooked Pathogens with Non-Negligible Clinical Relevance BUTCHER Sarah - A Conserved, Novel, Druggable Interprotomer Pocket in Enterovirus Capsids NAISMITH James - Structural Biology in a Pandemic GOULET Adeline - CRISPR-Cas9 Allosteric Inhibition by the Viral Anti-CRISPR Protein AcrIIA6

Program
 

Aim & Scope

The recent pandemic outbreak of COVID-19 caused by the SARS-CoV-2 virus showed quite clearly that viral diseases in human, but also in animals and plants, are an emerging threat to modern societies. The need of research in this area has received additional support by the fact that the Noble Prize for medicine 2020 had been awarded to the discovery of the hepatitis C virus, which enabled the “development of blood test that have saved millions of lives”. Fundamental research was and is challenged to act rapidly to push developments towards new diagnosis methods and medication especially in case of an epidemic or even pandemic context. At current, medication is available for relatively few human-pathogenic viral infections like influenza, varicella-zoster, hepatitis, HIV and others. Many other viral infections can, up-to-date, not be treated properly. Therefore, more research is needed and is only possible through a multi-disciplinary approach resulting in a profound understanding of the virus itself, the exact way(s) of infection and the developments of drugs based on the atomic structures of viral proteins. Towards this theme, experts in viral research will be presenting their cutting-edge research during this micro-symposium.