Structural Biology - Rolling Access

CryoEM can be used for protein structure determination with near atomic resolution by single-particle analysis or by cryo-electron tomography.

Sufficient proof of the sample’s quality must be included with the proposal. The project description template is limited to a maximum of 4 pages: 2 pages for the project description and a further 2 pages to provide evidence of the sample’s quality.

Rolling access proposals will normally be reviewed electronically by the Proposal Review Panels within 3 weeks of submission, and if beamtime is awarded this will typically be scheduled within 6-8 weeks from submission.

Experiment Reports on previous experiment(s) must be systematically submitted via the ESRF User Portal, and indicated on the Rolling proposal form as "Relevant Reports". The Proposal Review Panel will not allocate beamtime to new Rolling proposals if experiment reports on past proposals have not been submitted.

1

Submit the online request for beamtime Create a new proposal. Fill the different parts of the proposal: Proposal form. Declare all samples for your proposal. Complete the appropriate “Rolling project description” form (templates below) and upload it as a pdf file to your online proposal. Submit the proposal - remember to check the content by clicking on the pdf link before submission as no further editing will be possible after submission. Your proposal will immediately be assigned a final Proposal_ID (e.g. "MX-XXXX") and transmitted electronically to the internal and external reviewers.

2

If approved and awarded beamtime: Register any additional sample sheets for the samples to be studied using the “Manage Samples” action of the proposal.

Templates Required

Maximum size of Rolling XRD project description: 2 pages
Maximum size of Rolling BioSAXS project description: 2 pages
Maximum size of Rolling SSX & TR-SSX project description: 2 pages
Maximum size of Rolling CryoEM project description: 4 (2+2) pages